Andrew Nicolaides (Greek: Ανδρέας Νικολαΐδης; born 1938) is a British-Greek Cypriot surgeon, and an expert in cardiovascular disease and stroke prevention.
[2] Nicolaides has undertaken research on venous thromboembolism,[3] noninvasive vascular investigations with particular emphasis on venous disease, the cardiac assessment of the arteriopath and more recently carotid plaque (atheroma) characterisation,[4] identification of patients at increased risk for stroke and stroke prevention.
[9] The measurements of ejection fraction of the calf muscle pump and reflux in ml/s opened the door towards a better understanding and classification of chronic venous disease.
In the mid-1990s, Nicolaides developed the method of normalising ultrasonic vascular images so that reproducible measurements of echodensity and texture can be made.
[12] He was the organiser and coordinator of the multicentre Asymptomatic Carotid Stenosis and Risk of Stroke (ACSRS) prospective natural history study.
The multidisciplinary approach combining angiography, high-resolution ultrasound, thrombolytic therapy, plaque pathology, histochemistry, coagulation studies, and more recently molecular biology has led to the realisation that carotid plaque rupture is a key mechanism underlying the development of cerebrovascular events.