The Anglesea River rises in the Otway Ranges east of Winchelsea and flows generally east by south before reaching its mouth and emptying into Bass Strait near the town of the same name.

In the Aboriginal Australian Wathawurrung language the name for the river is Kuarka-dorla, meaning "place to catch mullet".

[4] The river was named after Anglesey, an island in Wales.

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