The reproducibility of animal test results in biomedical research has been questioned repeatedly in the past.
In order to increase the transparency and the quality in the field of preclinical and basic research, the establishment of so-called centralized animal study registries was suggested.
[5][6] The publication bias was identified as one main reason for the lack of reproducibility of research results.
Registration of the study plan could reduce the publication bias and prevent practices like data dredging.
The detailed query of the methods as well as the statistical planning supports the scientists in the study preparation and can thus increase the quality of as well as the reproducibility of the animal experiments.