Anne of Ostfriesland (June 26, 1562 – April 21, 1621) was the eldest daughter of Count Edzard II of East Frisia and his wife, Catherine Vasa, daughter of Gustav I of Sweden.

Anne married three times: Anne had no living children by any of her husbands.

She was buried in the Church of the Holy Spirit, Heidelberg, but her grave is not preserved.

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