A shooting guard, Edwards played college basketball for the Georgia Bulldogs and was selected with the first overall pick by the Timberwolves in the 2020 NBA draft.

[3] Due to his success with the Atlanta Xpress 15-under Amateur Athletic Union team, Edwards was considered a four-star recruit by Rivals in 2016.

He made the move in an effort to improve his academic performance, since Holy Spirit Preparatory had "small class sizes and support to help that.

[11] In his senior season, his team finished as GISA Class AAA runners-up to The Heritage School, despite 27 points from Edwards.

[22] Sources: On November 5, 2019, Edwards made his debut for the Georgia Bulldogs, recording 24 points, 9 rebounds, and 4 steals in a 91–72 win over Western Carolina.

[23] On November 26, he scored a season-high 37 points, including 33 in the second half, and posted six rebounds, four steals, and three blocks in a 93–85 loss to third-ranked Michigan State at the Maui Invitational.

[24] In his final game at the tournament, he led all scorers with 24 points and made the game-winning shot against NCAA Division II team Chaminade.

[27] On February 26, Edwards scored 36 points and collected seven rebounds, four assists and four steals, in a 94–90 overtime defeat to South Carolina.

On December 23, 2020, he made his NBA debut, putting up 15 points, 4 rebounds, and 4 assists in 25 minutes, in a 111–101 win against the Detroit Pistons.

He became the youngest NBA player ever with 10 three-pointers in a game, breaking the previous record set in 2015 by Kyrie Irving at age 22.

[39] On January 25, 2022, in a 109–107 win over the Portland Trail Blazers, he became the first player in NBA history to record a stat line of at least 40 points, 9 rebounds, 3 blocks, 3 steals, and 5 three-pointers in a single game; he joined Carmelo Anthony as the only players to score 40 points without an assist at 20 years old or younger.

Edwards and De'Aaron Fox were announced as injury replacements for injured stars Stephen Curry and Zion Williamson.

[46] On April 9, in the final game of the 2022–23 season, Edwards recorded 26 points, 13 rebounds, 4 assists, 4 steals, and 4 blocks to help lead the Timberwolves to a 113–108 win over the New Orleans Pelicans, earning the eight seed in the Western Conference play-in tournament.

[47] In Game 2 of the Timberwolves' first-round playoff series against the Denver Nuggets, Edwards put up 41 points in a 122–113 loss.

[49] In Game 4, Edwards had 34 points, 6 rebounds, 5 assists, 2 steals, and 3 blocks and scored a crucial 3-pointer to lead the Timberwolves to a 114–108 overtime win.

[50] In Game 5, the Timberwolves were eliminated from the playoffs by the eventual NBA champion Nuggets despite 29 points, 8 rebounds, 7 assists, and 2 blocks by Edwards.

[57] In Game 4 of the first round of the playoffs against Phoenix, Edwards scored 31 of his 40 points in the second half, along with nine rebounds and six assists in a 122–116 win to close out the series.

[58][59] In Game 1 of the Western Conference Semifinals, Edwards scored a then playoff career-high and franchise postseason-record 43 points in a 106–99 victory over the Nuggets.

[60] In Game 4 of the Western Conference Semifinals, Edwards scored a playoff career-high and franchise postseason-record 44 points, along with five rebounds and five assists, in a 115–107 loss to the Nuggets.

[61] In Game 4 of the Western Conference Finals, Edwards posted a near triple-double with 29 points, 10 rebounds and 9 assists in a 105–100 victory over the Dallas Mavericks.

[64] On January 25, Edwards surpassed Karl-Anthony Towns for the most career three-pointers in Timberwolves franchise history with 976, in a 133–104 win over the Denver Nuggets.

[71] Edwards was a member of the United States national team that competed in the 2023 FIBA Basketball World Cup.

[78] Despite pre-draft concerns that he was a limited long-range scorer, Edwards has developed an efficient, high-volume three-point shot — shooting 36% on almost eight attempts per game.

[80] His ability to match up against both long wings and shifty guards has garnered praise from Timberwolves head coach Chris Finch.

[83] Edwards left the Timberwolves’ March 1 game against the Sacramento Kings at halftime to be with Aislynn's mother, Shannon, as their child was born.

[89] In September 2022, Edwards posted a video to Instagram story referring to a group of shirtless men standing on a sidewalk with a homophobic slur.