Anthony John King Mussio (June 13, 1902 – April 15, 1978) was an American prelate of the Roman Catholic Church.

He earned a doctorate in canon law in 1939 with a dissertation entitled "The Education of Offspring : a Primary End of Matrimony" [5] Following his return to Cincinnati in 1939, Mussio was appointed as assistant chancellor of the archdiocese.

[3] On March 10, 1945, Mussio was appointed the first bishop of the newly erected Diocese of Steubenville by Pope Pius XII.

[4] He received his episcopal consecration on May 1, 1945, from Archbishop McNicholas, with Bishops Michael Ready and George Rehring serving as co-consecrators, at St. Monica's Pro-Cathedral.

[3] In a 1960 article in the publication Ave Maria from the University of Notre Dame, Mussio said that existing parish structures were outdated and cumbersome.

In accord with the Council's reforms, he established the Steubenville Ecumenical Institute to foster better relationships among Christians and Jews.