[1] Clarence Issenmann worked as delivery boy and meat cutter for his father as young man.
He then entered the Pontifical University of St. Thomas Aquinas in Rome, Receiving a Doctor of Theology degree.
After returning to the United States, Issenmann entered Regis University in Denver, Colorado, where he received a Doctor of Journalism degree.
[1] Pope Pius XII appointed Issenmann as the sixth bishop of the Diocese of Columbus on December 5, 1957.
Attending the Second Vatican Council in Rome from 1962 to 1965, he also served as the assistant episcopal chair of lay organizations for the National Catholic Welfare Conference.
[1][2] As bishop, he constructed the following schools in the diocese: In November 1968, Issenmann asked all adults attending mass in the diocese to sign petitions of support for Humanae vitae, Pope Paul VI's 1969 encyclical against artificial birth control.