James Frederick Bryan Wood (April 27, 1813 – June 20, 1883) was an American prelate of the Roman Catholic Church.

[3] In November 1827, he and his family removed to Cincinnati, Ohio, where the young Wood became a clerk at the Branch Bank of the United States.

After being advanced to individual book-keeper and discount clerk, he was made a paying and receiving teller (1833) and cashier (1836) in the Franklin Bank of Cincinnati.

[1] Wood also developed a friendship with Bishop John Baptist Purcell, who later baptized him into the Catholic Church on April 7, 1836.

[2] In 1865 he purchased a large tract of land in Overbrook, on the outskirts of Philadelphia, for the new St. Charles Borromeo Seminary, the cornerstone of which was laid on April 4, 1866.

[1] He also determined that those Sisters of St. Francis of Philadelphia based in Syracuse, New York should establish a separate daughter congregation.

[5] Wood attended the First Vatican Council, where he supported the definition of papal infallibility,[1] but was forced to leave early in March 1870 due to poor health.

[3] He traveled to Rome in 1877 to assist at the celebration of the golden jubilee of Pius IX's episcopate, but returned home after suffering from a severe attack of rheumatism.

In 2014, St. Charles Borromeo Seminary decided to sell an 1877 portrait of Archbishop Wood painted by Thomas Eakins.