John Henry Luers (September 29, 1819 – June 29, 1871) was an American prelate of the Roman Catholic Church.

[2] In 1835, Luers' outlook towards Catholicism and service to others changed after meeting Archbishop John Baptist Purcell.

"In the evening, at nearby St. Joseph Church, Luers’ parishioners hosted a reception for their longtime pastor.

On this occasion, they presented him with a mitre, crosier, pectoral cross, bishop’s cassock, ambry with episcopal seal, three pairs of pontifical shoes, and $1,200.

In 1868, Luers established an orphanage in Rensselaer, Indiana, for children who had lost their parent during the American Civil War.

While returning to the Cleveland train station on June 29, John Luers suffered a fatal stroke.

At the time of Luers' death, the Diocese of Fort Wayne had 69 priests, 75 churches, ten chapels, one hospital, one orphan asylum, one college, 11 academies for girls, 40 parochial schools, and a Catholic population estimated at 50,000.