'quadrant'; Spanish: Antisuyo)[1][2] was the eastern part of the Inca Empire which bordered on the modern-day Upper Amazon region which the Anti inhabited.

[1] Antis is a collective term for the many varied ethnic groups living in the Antisuyu such as the Asháninka or the Tsimané.

[6] 'Anti' is the likely origin of the word 'Andes', Spanish conquerors generalized the term and named all the mountain chain as 'Andes', instead of only the eastern region, as it was the case in Inca era.

According to some sources, Antisuyu was not the smallest of the Incan suyus, citing that its territory may have included the eastern slope of the Tahuantinsuyu as well as the adjoining tropical lowlands along the length of the empire.

Historian Andrew Nicol published research in 2009 in which he concluded that the existence of a city such as Paititi is possible within the Peruvian Amazon Basin.