[1] Carini showed that rabies of herbivores could be transmitted by bats, and discovered a parasitic fungus (Pneumocystis carinii, now known as P. jirovecii), which causes pneumocystosis.
In 1909, examining the lungs of guinea pigs experimentally infected with Trypanosoma cruzi, Carlos Chagas described parasitic forms that linked the pulmonary cycle of the trypanosome.
But in 1910, Carini and Maciel Jesuino found cyst formations very similar to these parasitic forms when examining the lungs of rats living in the sewers and naturally infected by Trypanosoma lewisi.
Carini sent the biological material from São Paulo to French researchers Pierre and Eugénie Delanoë at the Institut Pasteur in Paris.
In 1942, two Dutch researchers, G. van der Meer and S. L. Brug, were presented three cases in humans (two babies and a 21-year-old adult), affected by a form of pneumonia particularly frequent in Central Europe, especially in frail or dystrophic premature children.