He first appears in the historic record in 1501 in Bruges, at the church of St. Donatian, where he taught singing to the choirboys.
He took a similar musical post in Mechelen at the church of St. Rombout in 1504, but he had fallen into debt, and left his job in a hurry in 1505, evidently fleeing from bill collectors.
His next documented appointment was in 1510 when he was singing master for the chapel of Anne of Brittany; and when the singers were absorbed by the French court after her death in 1514, he went with them, and stayed in the French court chapel until at least 1525, when François I was decisively defeated and captured at the Battle of Pavia.
Surviving works by Divitis include masses, motets, Magnificat settings (a genre that was to become quite popular in the middle 16th century), and a chanson.
The three masses by Divitis use parody technique, and are among the first to do so; he is cited as influential in development of the genre, along with Jean Mouton and the other members of the French royal chapel.