No harmful effects have been specifically associated with mono- and diglycerides.” There are publicly available documents, like a GRAS submission and patents, that Apeel submitted early in their R&D stages that describe the use of solvents.

Ethyl Acetate – A solvent commonly used in food processing but also associated with potential central nervous system effects if present in high quantities.

[3][7] Edipeel is also allowed for use on all fruits and vegetables in Canada, Chile, China, Colombia, Japan, Kenya, Mexico, Peru, and South Africa, without restriction.

[8] Apeel was founded in 2012 by James Rogers,[3] after receiving a $100,000 grant from the Bill and Melinda Gates Foundation to help reduce post-harvest food waste in developing countries that lacked refrigeration infrastructure.

However, the US FDA, global regulatory agencies, and other food and nutrition experts have affirmed the safety of Apeel’s products for consumption by consumers.

[20] Agricultural feedstocks have naturally occurring levels of heavy metal impurities due to the uptake of these substances from the surrounding soil, air, and water.