Apostolos Serletis lives in Calgary, Alberta, Canada with his wife Aglaia.

His research draws from a large number of areas, such as macroeconomics, monetary economics, flexible functional forms and demand systems, and nonlinear and complex dynamics.

Serletis also Canadianized a number of leading U.S. text books, including Financial Markets and Institutions (with Frederic Mishkin and Stanley Eakins), The Economics of Money, Banking, and Financial Markets (with Frederic Mishkin), Macroeconomics: A Modern Approach (with Robert Barro), and Principles of Economics (with Glenn Hubbard, Anthony O'Brien, and Jason Childs).

He is a Fellow of the Royal Society of Canada, President of the Society for Economic Measurement, Co-Editor of Macroeconomic Dynamics (Cambridge University Press) and the Journal of Economic Asymmetries (Elsevier), Editor-in-Chief of the Open Economies Review (Springer), and Associate Editor of Energy Economics (Elsevier).

He has also edited a number of scholarly collections, including a special issue of the prestigious Journal of Econometrics with James Heckman, the 2000 Nobel Laureate of the University of Chicago.