Appleton is an unincorporated community in Allendale County, in the U.S. state of South Carolina.

[1] Appleton was founded in 1872 when the railroad was extended to that point, and was named after a railroad agent.

[2] A post office called Appleton was established in 1872, and remained in operation until 1960.

[3] In 1925, Appleton had 234 inhabitants.

This South Carolina state location article is a stub.