Aquone is an unincorporated community in Macon County, North Carolina, United States.

Aquone is located near the Nantahala River, 29 miles (47 km) west of Franklin.

[1] Aquone had a post office until it closed on January 12, 1996.

[2] The community's name is derived from the Cherokee word egwanul'ti, meaning "by the river".

This article about a location in Macon County, North Carolina is a stub.