A second segment of 4.29 miles (6.90 km) runs from US 70 in West Memphis north to US 64 in Marion.

Both routes are maintained by the Arkansas State Highway and Transportation Department (AHTD).

Highway 118 begins at US 64 in the northeast corner of Earle within Crittenden County in the Arkansas Delta.

The highway passes three historic properties and continues north before turning due east and entering Mississippi County.

The highway continues north to Marion, running along the western city limits before an intersection with US 64.