It was renumbered to 130 to prevent confusion with Interstate 30 in 1958, and the segment between North Little Rock and Stuttgart was replaced by an extension of US 165 in 1981, producing the current alignment.

[a] The route is a rural, two-lane road its entire length, except near the western terminus in Stuttgart.

[2] Highway 130 is entirely within the Grand Prairie, a subset of the Mississippi Alluvial Plain ecoregion known for rice cultivation and duck hunting.

Highway 130 continues east through a commercial area as a four lane divided highway with a paved median, crossing a railroad spur before an intersection with US 165 (Park Avenue) near the Riceland Foods headquarters.

Continuing east, Highway 130 becomes a two-lane road, passing residential subdivisions and the Stuttgart Country Club before entering an agricultural part of Arkansas County.

[5] Near the University of Arkansas System Arkansas Agricultural Experiment Station Rice Research Extension Center and United States Department of Agriculture's and Harry K. Dupree Stuttgart National Aquaculture Research Center, Highway 130 serves as the northern terminus of Highway 153, with Highway 130 turning south toward Almyra.

South of the intersection, Highway 130 passes the L.A. Black Rice Milling Association Inc. Office, which is listed on the National Register of Historic Places (NRHP),[7] and the DeWitt Cemetery before an intersection with Highway 1 Business, where it terminates.

[13] The designation was approved on October 3, 1981, by the United States Route Number Committee of the AASHTO, truncating Highway 130 to the current northern terminus.

Highway 130S continues east past residences and churches, turning south and the post office onto Columbia Street.

State maintenance ends at a t-intersection with 14th Street, an unpaved road along the southern town limits.

[22] In 1953, the segment west of US 65 was redesignated as Highway 9, trimming the route to approximately 1 mile (1.6 km).

130A) is a former planned state highway alternate route in DeWitt, Arkansas.