One route of 13.3 miles (21.4 km) begins at US Highway 79 (US 79) near Humphrey and runs east to US 165.

A third route of 7.5 miles (12.1 km) begins at US 165 and AR 267, and the Great River Road (GRR) and runs east to Highway 17.

All routes are maintained by the Arkansas State Highway and Transportation Department (AHTD).

AR 152 begins at US 79 east of Humphrey in western Arkansas County on the Grand Prairie.

The route passes a residential neighborhood before intersecting AR 130 (Monroe Street).