[1][2][3] Highway 26 begins in rural Howard County, about 7 miles (11 km) east of the city of Lockesburg.

For about 12.4 miles (20.0 km), the route continues to head east before intersecting with Highway 27 southwest of Murfreesboro.

From there, the route continues to head east, traveling through the towns of Delight and Antoine.

The route continues heading west for about one more mile (1.6 km) before ending at the entrance to the Alcoa plant east of Gum Springs.

[5] Arkansas Highway 26 Spur is a spur route, which is about 1.2 miles (1.9 km) long and mainly runs along the corridor of the Clark County Industrial Park south of Gum Springs in Clark County.