The two routes form a brief concurrency eastward, before Highway 335 turns north on Wyatt Drive.

The highway passes through a flat, forested area typical of the Gulf Coastal Plain, sparsely populated with residences, churches, and three cemeteries.

East of the town, Highway 335 winds through a sparsely populated rural area, crossing Haynes Creek before terminating at US 167.

ArDOT estimates the traffic level for a segment of roadway for any average day of the year in these surveys.

As of 2016, the highest estimated count was between Highway 7 and Norphlet, with 2,000 vehicles per day (VPD).

The route started at a diamond interchange with US 82 and Highway 15 in southwestern El Dorado.