One segment begins at Highway 1 Business (AR 1B) in Forrest City and runs southeast to Tuni.

The highway winds southeast toward the Lee County line through Crowley's Ridge.

The loess hill terrain makes the route wind and curve more than the surrounding highways in St. Francis County covering the Mississippi Alluvial Plain.

[3] As of 2016, the route had an annual average daily traffic (AADT) of 1,500 vehicles per day (VPD) within Forrest City, but 270 VPD east of the city, earning a classification as a very low volume local road by the American Association of State Highway and Transportation Officials (AASHTO), meaning fewer than 400 vehicles per day.

[4] Highway 334 begins at US 79 on the St. Francis-Lee County line in the Arkansas Delta.