ArDOT estimates the traffic level for a segment of roadway for any average day of the year in these surveys.

The route runs north, passing under the Union Pacific Railway tracks before serving as the southern terminus of AR 195 (Ogan Street).

[10] AR 355 exits the community northbound, passing within a few miles of the Little River Wildlife Management Area (WMA), Nacatoch Ravines Natural Area, and the John W. Turk Jr. Coal Plant before entering McNab, where it crosses the Kiamichi Railroad tracks.

The route continues north toward Saratoga, winding through the Piney Woods to serve as the southern terminus of AR 73 before crossing into Howard County.

The route continues north along the east side of Lake Millwood before entering the small town of Tollette.

AR 355 intersects US 371 approximately 4 miles (6.4 km) west of Nashville before winding north to a junction with US 278, where it terminates.

[11] The roadway continues east as Hempstead County Route 8 (CR 8, HP Powell Road).

The route runs east through a rural area to the small town of Patmos before winding into Nevada County.

Continuing southeast, AR 355 passes through Falcon Bottoms Natural Area and crosses Dorcheat Bayou before entering Columbia County.