Once the Arsacids, in the person of Vologases II (r. 180-191), had consolidated their hold on the Armenian throne by 180, they gained momentum to interfere in Iberia.
[1] Even as the Arsacids set on the thrones of three Caucasian kingdoms – those of Armenia, Iberia, and Albania – the dynasty was dislodged, in 226, from power in its original homeland and the more powerful and dynamic Sassanid dynasty emerged as new masters of the Iranian Empire.
Although the later Georgian chronicles documents this change of power, its account of that period is full of anachronisms and semi-legendary allusions, providing little or no details about the effect of Iranian resurgence on Arsacid Iberia.
Shapur I (r. 242-272) placed a vassal, Amazaspus III (r. 260-265), on the throne of Iberia, possibly a rival or anti-king of Mihrdat II.
In 284, with the death of Aspagur I, the Iberian Arsacid line ended, and the Sassanids capitalized on a civil strife in the Roman Empire to establish their candidate, Mirian III, of the Chosroid dynasty, on the throne of Iberia.