Lefkaditis was born in 1872 to parents from Argostoli on Cephalonia in the Ionian Islands in western Greece.
His love for sports led him to become director of the Panhellenic Gymnastics Association and working with professor and school owner Dimitris Makris (Δημήτρης Μακρής).
During the 1908 Summer Olympics in London, as a member of the Greek delegation, Lefkaditis observed with interest the British Scouts' service and activities at the Games.
He met with Robert Baden-Powell and shortly after, introduced Scouting in Greece in 1910.
Mention of him may be found in a number of other books related to Greek Scouting as well.