The men's 4 × 100 metre relay event at the 2008 Olympic Games took place on 21 and 22 August at the Beijing National Stadium.

On 25 January 2017, the Jamaican team was stripped of the gold medal place due to Nesta Carter testing positive for the prohibited substance methylhexaneamine.

[3][4][5] The IOC requested that the IAAF modify the results, and, after CAS dismissed the appeal of the Jamaican team,[6] the medals were redistributed accordingly.

[7] Trinidad and Tobago team was advanced to gold, Japan to silver, and Brazil to bronze.

Prior to this competition, the existing world and Olympic records were as follows.