The Women's 400m athletics events for the 2020 Summer Paralympics took place at the Tokyo National Stadium from August 27 to September 4, 2021.

The final in this classification took place on 31 August 2021, at 11:36:[4] The T13 category is for athletes with a moderate visual impairment.

Athletes in this category have a variety of visual impairments, but can typically recognize contours from a distance of 2 to 6 metres.

The final in this classification took place on 31 August 2021, at 20:38:[6] The T37 category is for ambulant athletes with cerebral palsy.

The final in this classification took place on 4 September 2021, at 20:38:[8] The T47 category is for athletes who have a single below elbow or wrist amputation or similar disability, with normal function in both legs.