He also played for the Los Angeles Rams, Kansas City Chiefs, and Seattle Seahawks.

As a senior, he aided the Hawkeyes to a 12–0 start, earning a spot in the Big Ten Championship and the 2016 Rose Bowl.

He was a finalist for the Rimington Award, which is given annually to the nation's top center, in his senior season.

[9][10] Blythe entered the 2018 season as the starting right guard after incumbent starter Jamon Brown was suspended the first two games of the year.

[15] Blythe is a graduate of Williamsburg (Iowa) High School, where he was a two-time all-state football player at center and a three-time state champion in wrestling.