In molecular biology, autophagy related 3 (Atg3) is the E2 enzyme for the LC3 lipidation process.
The activated intermediate, LC3-Atg3 (E2), is recruited to the site where the lipidation takes place.
Autophagocytosis is a starvation-induced process responsible for transport of cytoplasmic proteins to the lysosome/vacuole.
[6] The small C-terminal domain is likely to be a distinct binding region for the stability of the autophagosome complex.
[7] It carries a highly characteristic conserved FLKF sequence motif.