Autosome

For example, the SRY gene on the Y chromosome encodes the transcription factor TDF and is vital for male sex determination during development.

[4] All human autosomes have been identified and mapped by extracting the chromosomes from a cell arrested in metaphase or prometaphase and then staining them with a type of dye (most commonly, Giemsa).

For example, the karyogram of someone with Patau Syndrome would show that they possess three copies of chromosome 13.

Aneuploidy of autosomes is not well tolerated and usually results in miscarriage of the developing fetus.

If the duplication or deletion is large enough, it can be discovered by analyzing a karyogram of the individual.

Autosomal translocations can be responsible for a number of diseases, ranging from cancer to schizophrenia.