She was discovered by actor Coco Martin, who saw her potential in the primetime television series FPJ's Ang Probinsyano (2016–2019),[5] a remake of the 1997 film of the same title and name.
Briguela gained widespread for her role as "MakMak" and the series was produced by Dreamscape Entertainment Television, who created many successful pictures such as Doble Kara, Ina, Kapatid, Anak, and Till I Met You.
Briguela starred in the series opposite Coco Martin, Susan Roces, Maja Salvador, Bela Padilla, Albert Martinez, Arjo Atayde, Eddie Garcia, Agot Isidro, Jaime Fabregas, and Simon "Onyok" Pineda, who played the role of Onyok.
She made her feature film debut in the Super Parental Guardians (2016) where she portrayed the role of Megan Gaspar alongside fellow Ang Probinsyano actors Coco Martin, Onyok Pineda and Vice Ganda.
Raised as a boy, her parents said that she has already shown signs of "being gay" since she was three years old for expressing preference for Barbie, Hello Kitty and skirts.