Aylesbury High Street railway station was the London and North Western Railway station which served the town of Aylesbury in the English county of Buckinghamshire.

It was the terminus of a branch from Cheddington on what is now known as the West Coast Main Line running to London Euston and to Birmingham New Street and further north.

British Railways (BR) renamed the station Aylesbury High Street on 25 September 1950; it was then closed to passengers on 2 February 1953[3] and then freight on 2 December 1963.

During the summer of 2015 trees and vegetation were cleared from the formation in preparation for the construction of a new Stocklake (urban) road.

This will be converted into a new service road for homes and businesses, providing more parking and easier access.