Azadiradione is a naturally occurring compound found in several plants, most notably the neem tree (Azadirachta indica).

Smaller quantities of azadiradione can also be found in other plants like Cedrela odorata (Spanish cedar), Chisocheton siamensis, Xylocarpus granatum (cannonball mangrove) and Azalea indica (common azalea).

Azadiradione acts as an antioxidant and has been used in traditional medicine in Asia, Africa and the Middle East for ages.

[1] Research suggests azadiradione may have properties that fight microbes (bacteria, fungi, viruses),[2] reduce inflammation, protect cells from damage,[3] and even have anti-cancer effects.

[4][5][6][7] Azadiradione may also act as a natural pesticide, potentially controlling some insects and pests.