It is 318 kilometres (198 mi) long and connects the capital Windhoek with the Buitepos border crossing to Botswana.

Gobabis, the capital of Omaheke Region, lies on the B6, as do the villages of Seeis, Omitara and Witvlei.

Hosea Kutako International Airport is also located on the B6, east of Windhoek.

The entire length of the B6 is part of the Trans-Kalahari Corridor route that connects the Namibian harbour town of Walvis Bay via Botswana with Pretoria, the capital of South Africa.

The territory had a total of only 5 motor vehicles at that time, and transport by motor vehicle only increased significantly with the deployment of South African troops during World War I.