Originally anchored by Pia Arcangel and Raffy Tima, it premiered on November 11, 2005, on QTV.

On April 25, 2011, Grace Lee joined as the new host for the segment Star Bites.

[1] On August 2, 2019, Jun Veneracion left Balitanghali Weekend, followed by Mariz Umali two days later.

[2][3] In March 2020, the production was temporarily halted due to the enhanced community quarantine in Luzon caused by the COVID-19 pandemic.

[5] In February 2021, GMA News TV was rebranded as GTV, with the show being carried over to the said network.