The school competes in the Mid-American Conference in Division I of the National Collegiate Athletic Association (NCAA).

The Cardinals play home basketball games at Worthen Arena on the Ball State campus in Muncie, Indiana.

[3][4][5] Ball State has won the Mid-American Conference women's basketball tournament once, in 2009, while finishing as runner-up in 2002, 2003, 2007, and 2014.

[6] They have won the MAC West Division in 2002, 2003, 2007, 2008, 2009, 2015 while finishing as regular season champions in 2002 and 2003.

[7][8] On December 21, 2017, the Cardinals defeated Western Kentucky and remained undefeated in non-conference play for the first time in school history.