Barbara J. Grosz CorrFRSE (Philadelphia, July 21, 1948) is an American computer scientist and Higgins Professor of Natural Sciences at Harvard University.

Grosz was elected a member of the National Academy of Engineering in 2008 for pioneering research in natural language communication between humans and computers and its application to human-computer interaction.

[4][5] Grosz established and led interdisciplinary institutions, and advanced the role of women in science.

[21] Grosz contributed one chapter to the 2018 book Architects of Intelligence: The Truth About AI from the People Building it by the American futurist Martin Ford.

[22] She chaired the National Academies of Sciences, Engineering, and Medicine committee that produced the 2022 report Fostering Responsible Computing Research: Foundations and Practices.