Barton Road is a major arterial road linking central Cambridge, England with Junction 12 of the M11 motorway to the southwest.

Within Cambridge, Wolfson College, one of the University of Cambridge colleges, is located on the north side of the road, to the west of the junction with Grange Road.

St Mark's Church is located on Barton Road, a brick church designed by R. Philip Day and built 1902–03.

Off this road just to the south of Barton Road are the Cambridge Rugby Football Ground (West Renault Park, home ground of Cambridge Rugby Union Football Club), Trinity New Field, Pembroke College Sports Ground, and behind that St Catharine's College Sports Ground.

Gonville & Caius College's sports ground is at the Eastern end of Barton Road.