After several months of captivity, Duane is released by Granny Ruth, who is preparing to take everyone on a road trip to the home of her ex-husband, Doctor Hal Rockwell.
While traveling via bus to Hal's house in Peachtree County, the group stops at a drug store, where Granny Ruth meets local sheriff Andrew Griffin while Duane, attempting to wriggle out a bus window, meets the sheriff's daughter Opal, whom he tries to convince to help Belial and him escape.
At the police station, Sheriff Griffin finds his daughter in the midst of trying to seduce Duane in dominatrix attire and sends her away, shortly before Bailey and Baxter arrive with the babies.
Griffin sends Bailey and Baxter back to their homes and goes off to see what is going on at the Rockwell residence, leaving Officers Brennan, Banner, and Brody in charge of the station.
Flailing about in his armor, Belial scores a hit against Sheriff Griffin, who is swarmed and killed by the babies when he falls into their cradle.
Speaking into the camera, Granny Ruth tells the world that the freaks will no longer hide in the shadows and will fight back if oppressed.
Variety wrote, "Henenlotter's mix of wild over-acting, cartoon color scheme and heavy-handed message regarding tolerance is tough to take for the uninitiated.