[6] A Texian force was organized at the Manuel N. Flores ranch in Seguin that pursued and ensured Vasquez's flight from Texas.

[7] In June a smaller force under the command of Colonel Antonio Canales Rosillo raided southern Texas until being repulsed in an engagement near Fort Lipantitlan, west of Corpus Christi.

[8] French Mexican General Adrián Woll commanded the September expedition which included 500 cavalry, 900 infantry, 200 Cherokee scouts and two artillery pieces.

Mayor John William Smith assigned Captain Salvador Flores to command 100 local Tejanos against the Mexican invaders.

Colonel Mathew Caldwell, a veteran of the Texas Revolution who had just recently been released after capture during the Santa Fe Expedition, began forming a contingent in Seguin.

Caldwell never anticipated victory but knew that from their protected position his men could cause considerable damage to the Mexicans without being too exposed to enemy fire.

The Mexican cavalry attempted to cut Hays' command off from the right but the Texians managed to get back to the Salado, closely pursued.

After seeing the Texian camp, the cavalry chose to break off the pursuit and form a line of battle on the opposite side of the creek, in the prairie southeast of Caldwell's men.

The battle took the form of skirmishing for several hours as Caldwell directed his sharpshooters to constantly harass the Mexican line, then retreat back to the creek before being discovered.

Eventually General Woll ordered a full attack with his left and right wings, and so the Mexicans advanced; but they were repulsed within fifteen minutes.

[12] Caldwell pursued Woll's force after learning of the retreat and eventually caught up with them at the Hondo River where another battle was fought.

In it, Captain Hays captured the enemy artillery but was repulsed soon after by an overwhelming Mexican force who then continued the retreat towards the Rio Grande.

Captain Nicholas Dawson was leading a force of fifty-three men on September 17 to reinforce Caldwell when he was attacked outside of San Antonio by several hundred Mexican cavalrymen and Cherokee Indians, after a skirmish the Texians began to surrender and when they had been relieved of their weapons, the Mexicans opened fire again.