The Battle of Saltillo (October 25, 1840) was fought between insurgents under the command of Colonel Samuel Jordan fighting for the Republic of the Rio Grande and the Centralists under the command of General Ráfael Vásquez fighting for the First Mexican Republic.

[1] While official recognition from the Republic of Texas was not obtained, General Canales' tour was met with some success.

[2] General Canales sent Colonel Jordan and approximately 90 Texan volunteers south into disputed territory in late June; they crossed the Rio Grande, and took Ciudad Victoria, the capital of Tamaulipas, without any resistance.

A few of those who were guiding Jordan were still loyal to the Central government of Mexico and were trying to lead the Texans towards San Luis Potosí, where a Mexican ambush awaited.

Jordan suspected such and diverted his troops to Saltillo, Coahuila, where, on the 25 October he was attacked by Mexican General Ráfael Vásquez.