The road comes to a bridge over a CSX railroad line at the State Street junction, with the railroad line running parallel to the south, and passes between the Erie Maritime Museum to the north and the UPMC Hamot hospital to the south.

After intersecting Holland Street, the Bayfront Parkway heads south of the Erie Intermodal Transportation Center serving Erie Metropolitan Transit Authority buses and crosses a railroad spur from the CSX line.

The roadway heads away from the parallel CSX tracks and widens to four lanes, running northeast between the Erie Wastewater Treatment Plant to the north and the site of Fort Presque Isle to the south.

The roadway heads through residential areas with some commercial development and intersects PA 5 Alt.

[5] As of 2017[update] a project on the Bayfront Parkway is underway "to improve the pedestrian, bicycle, transit, and passenger vehicle connection of the Erie Central Business District and adjacent neighborhoods to the waterfront property north of the Bayfront Parkway (SR 4034), to reduce crashes as much as practical on the Bayfront Parkway, to improve future congestion to an acceptable level of service or delay, and to improve traffic operations and efficiency.