She studied with Benedetto Lupo at the Nino Rota Conservatory of Music in Monopoli and Arie Vardi at the Hochschule für Musik, Theater und Medien Hannover in Hanover, Germany.

Her recordings of the Tchaikovsky First and Prokofiev Second concertos and Bach's Goldberg Variations contributed to her winning the 2017 Gramophone Classical Music Awards Young Artist of the Year.

[6] In 2018 she was nominated for the Classic Brit Awards in the "Best Female Artist of the Year" category for her recording of Bach's Goldberg Variations.

[7] In October 2018, Rana made her debut in Amsterdam with the Royal Concertgebouw Orchestra.

[9] On 12 March 2019, Rana made her Carnegie Hall debut, playing Chopin's Twelve Etudes, Op.