The 2005–06 Belarusian Cup was the 15th edition of the football knock-out competition in Belarus.
Contrary to the league season, the competition has been conducted in a fall-spring rhythm.
The first games were played on 14 June 2005 and the final on 27 May 2006.
BATE Borisov won the Cup.
16 winners of previous round were joined by 14 clubs from Premier League.