[12][13] Bixby made her professional debut for the Thorns on June 27, 2020, in the 2020 NWSL Challenge Cup, a 2–1 loss to the North Carolina Courage.

[6][14][15] After posting two clean sheets in her first four games for the club, she suffered an ACL injury that forced her to miss the rest of the Challenge Cup.

Her 10 regular- and post-season shutouts led all NWSL goalkeepers, and her 0.96 average goals conceded per match trailed only Phallon Tullis-Joyce.

[20][21][22] On April 29, 2023, Bixby scored the game-tying goal in stoppage time in a home match against Angel City FC, securing a 3–3 draw.

[25] She did not appear for Frankfurt before suffering a right wrist injury, and on October 16, 2018, the German club announced that Bixby would return from her loan to Portland early for recovery.

[26] In 2022, Bixby returned to Rex Putnam High School to serve as the girls' varsity soccer team's head coach.

[29] In early July 2021, she called for the league to drop the "W" from its name, stating that it was both non-inclusive and that it promoted the misconception that the women's side of the game was abnormal.

[33] Five days prior to Thorns FC's November 14 match against Chicago Red Stars in the 2021 NWSL playoff semifinals, Bixby's father Dean died by suicide.