In 1819, on one voyage to India, she was anchored at Calcutta and the venue for a party that resulted in her captain, surgeon, and about a fifth of the guests all dying within days of an unknown disease.

British ships were then free to sail to India or the Indian Ocean under a licence from the EIC.

In February 1817, Bengal, built at Greenock in 1815, Cuthbertson, master, sailed from Britain, bound for Bombay.

On 12 June 1819, Bengal, built at Greenock in 1815, G. Woodward, master, sailed for Fort William, India.

Around 23 September she returned to Calcutta to effect repairs after having sustained damage in the Hooghli on her way to Liverpool.

"Effluvia" from the 17,000 buffalo horns that made up her cargo, was suspected, but this suspicion did not arise until after Bengal had sailed and could not be conveyed to her.

Lloyd's Register's list of licensed voyages reported that on 3 June 1824 Bengal, Pearce, master, had sailed for Calcutta.