Skin irritation may occur through industrial exposure, and florists, mushroom pickers and floriculturists have reported allergic reactions to benomyl.

[citation needed] In a laboratory study, dogs fed benomyl in their diets for three months developed no major toxic effects, but did show evidence of altered liver function at the highest dose (150 mg/kg).

[citation needed] In October 2008, DuPont paid confidential settlements to two New Zealand families whose children were born with various birth defects.

[citation needed] In 1991, DuPont issued a recall of its Benlate 50DF formula due to suspected contamination with the herbicide atrazine.

[citation needed] After several years of legal argument, DuPont paid out about US$750 million in damages and out-of-court settlements.

[citation needed] After carrying out tests, DuPont denied Benlate was contaminated with dibutylurea and sulfonylureas and stopped compensation pay-outs.

[citation needed] Benomyl is used in molecular biology to study the cell cycle in yeast; in fact, the name of the protein class "Bub" (Bub1, etc.)