Benzophenone imine is an organic compound with the formula of (C6H5)2C=NH.
A pale yellow liquid, benzophenone imine is used as a reagent in organic synthesis.
[1] Benzophenone imine can be prepared by the thermal decomposition of benzophenone oxime:[2] Benzophenone imine can also be synthesized by addition of phenylmagnesium bromide to benzonitrile followed by careful hydrolysis (lest the imine be hydrolyzed):[3] This method is known as Moureu-Mignonac ketimine synthesis.
[5] Benzophenone imine undergoes deprotonation with alkyl lithium reagents.
[7] Buchwald-Hartwig amination involves coupling aromatic halide and amine to form carbon-nitrogen bonds with the help of palladium-based catalysts.