Benzoxazine

Benzoxazines are a group of isomeric bicyclic heterocyclic chemical compounds that consist of a benzene ring fused to an oxazine ring.

1,3-Benzoxazines can be synthesized by the Mannich reaction using a phenol, an amine, and formaldehyde.

[2] Benzoxazine rings form the central chemical structure of a number of pharmaceutical drugs including, for example, apararenone,[3] elbasvir,[4] and etifoxine.

[5] Polybenzoxazines, also called benzoxazine resins, are a class of polymers that are produced from the ring-opening polymerization of 3-phenyl-2,4-dihydro-1,3-benzoxazine monomers and its chemical derivatives.

[6] The main applications of polybenzoxazines are as adhesives and in fiber-reinforced plastics.

Chemical structures of several examples of benzoxazine isomers