He was born in Ioannina, northwestern Greece, center of the 17th-18th century Modern Greek Enlightenment.
He composed a manual named Σταχυολογία (Set of Gleanings), printed in 1686 in Venice.
This work introduced new teaching methods with a series of questions and answers on Greek grammar and was considered a create success in Greek education and especially among the schools of Ioannina.
[1][2] Makris got also involved in various theological discussions with another local scholar, Georgios Sougdouris, who succeeded him as head of the Goumas School in 1683.
[3] At 1699 he published the philosophical work Περί των τριών Αρετών Πίστεως Αγάπης και Ελπίδος (On the three Virtues: Faith, Love and Hope).